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Autoimmune Disorders
By:Kutty Selva Nandakumar
Published on 2019 by

Autoimmune diseases (ADs) occur when the immune system is mistakenly activated and attacks self antigens present in our body, leading to tissue destruction. Increasing prevalence of ADs is not only a problem for the affected patients but also causes enormous economic burden to the society. Genetic, environmental and epigenetic factors, and interactions between them contribute to the clinical disease outcome. Although most of these diseases are polygenic and multifactorial, and the clinical spectrum differs significantly between the ADs, shared genes and pathogenic pathways attacking specific tissues or organs do exist. Hence, better understanding of the immunological and pathological basis of these diseases will help to design early diagnostic methods, identify new drug targets, optimize treatments to alleviate sufferings of patients, and develop vaccines and methods to control progression of disease manifestations. This book is organized into seven chapters: Detailed description of Multiple Sclerosis (MS), Inflammatory Bowel Disease (IBD) and Psoriasis (Ps); Antibody mediated disease pathogenesis in Rheumatoid arthritis (RA) and type I diabetes (T1D), antibody glycosylation and its critical role in its effector functions; macrophages in inflammation and its resolution and, the use of nanoparticle-based drug delivery systems for ADs are discussed in detail.

This Book was ranked at 6 by Google Books for keyword autoimmune.

Book ID of Autoimmune Disorders's Books is hWubxgEACAAJ, Book which was written byKutty Selva Nandakumarhave ETAG "LyuE7mbkBBU"

Book which was published by since 2019 have ISBNs, ISBN 13 Code is 9781536160468 and ISBN 10 Code is 1536160466

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Book which have "288 Pages" is Printed at BOOK under CategoryAutoimmune diseases

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